AHCI RESEARCH GROUP
Publications
Papers published in international journals,
proceedings of conferences, workshops and books.
OUR RESEARCH
Scientific Publications
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2023
Su, Qiqi; Peretokin, Vadim; Basdekis, Ioannis; Kouris, Ioannis; Maggesi, Jonatan; Sicuranza, Mario; Acebes, Alberto; Bucur, Anca; Mukkala, Vinod Jaswanth Roy; Pozdniakov, Konstantin; Kloukinas, Christos; Koutsouris, Dimitrios D.; Iliadou, Elefteria; Leontsinis, Ioannis; Gallo, Luigi; Pietro, Giuseppe De; Spanoudakis, George
The SMART BEAR Project: An Overview of Its Infrastructure Proceedings Article
In: Maciaszek, Leszek A.; Mulvenna, Maurice D.; Ziefle, Martina (Ed.): Information and Communication Technologies for Ageing Well and E-Health, pp. 408–425, Springer Nature Switzerland, Cham, 2023, ISBN: 978-3-031-37496-8.
Abstract | Links | BibTeX | Tags: Ageing, AI, Balance Disorder, Cardiovascular Disease, Cloud, Evidence-based, GDPR, Healthcare, Hearing Loss, HL7 FHIR, Semantic interoperability
@inproceedings{suSMARTBEARProject2023,
title = {The SMART BEAR Project: An Overview of Its Infrastructure},
author = {Qiqi Su and Vadim Peretokin and Ioannis Basdekis and Ioannis Kouris and Jonatan Maggesi and Mario Sicuranza and Alberto Acebes and Anca Bucur and Vinod Jaswanth Roy Mukkala and Konstantin Pozdniakov and Christos Kloukinas and Dimitrios D. Koutsouris and Elefteria Iliadou and Ioannis Leontsinis and Luigi Gallo and Giuseppe De Pietro and George Spanoudakis},
editor = { Leszek A. Maciaszek and Maurice D. Mulvenna and Martina Ziefle},
url = {https://link.springer.com/chapter/10.1007/978-3-031-37496-8_21},
doi = {10.1007/978-3-031-37496-8_21},
isbn = {978-3-031-37496-8},
year = {2023},
date = {2023-07-14},
urldate = {2023-01-01},
booktitle = {Information and Communication Technologies for Ageing Well and E-Health},
pages = {408–425},
publisher = {Springer Nature Switzerland},
address = {Cham},
series = {Communications in Computer and Information Science},
abstract = {The paper describes a cloud-based platform that utilizes Artificial Intelligence (AI) and Explainable AI techniques to deliver evidence-based, personalized interventions to individuals over 65 suffering or at risk of hearing loss, cardiovascular disease, cognitive impairments, balance disorders, or mental health issues, while supporting efficient remote monitoring and clinician-driven guidance. As part of the SMART BEAR integrated project, this platform has been developed to support its large-scale clinical trials. The platform consists of a standards-based data harmonization and management layer, as well as a security component, a Big Data Analytics system, a Clinical Decision Support system, and a dashboard component to facilitate efficient data collection across pilot sites.},
keywords = {Ageing, AI, Balance Disorder, Cardiovascular Disease, Cloud, Evidence-based, GDPR, Healthcare, Hearing Loss, HL7 FHIR, Semantic interoperability},
pubstate = {published},
tppubtype = {inproceedings}
}
The paper describes a cloud-based platform that utilizes Artificial Intelligence (AI) and Explainable AI techniques to deliver evidence-based, personalized interventions to individuals over 65 suffering or at risk of hearing loss, cardiovascular disease, cognitive impairments, balance disorders, or mental health issues, while supporting efficient remote monitoring and clinician-driven guidance. As part of the SMART BEAR integrated project, this platform has been developed to support its large-scale clinical trials. The platform consists of a standards-based data harmonization and management layer, as well as a security component, a Big Data Analytics system, a Clinical Decision Support system, and a dashboard component to facilitate efficient data collection across pilot sites.
Basdekis, Ioannis; Kloukinas, Christos; Agostinho, Carlos; Vezakis, Ioannis; Pimenta, Andreia; Gallo, Luigi; Spanoudakis, Georgios
Pseudonymisation in the Context of GDPR-compliant Medical Research Proceedings Article
In: 2023 19th International Conference on the Design of Reliable Communication Networks (DRCN), pp. 1–6, IEEE, Vilanova i la Geltru, Spain, 2023, ISBN: 978-1-66547-598-3.
Abstract | Links | BibTeX | Tags: GDPR, Healthcare, Security
@inproceedings{basdekisPseudonymisationContextGDPRcompliant2023,
title = {Pseudonymisation in the Context of GDPR-compliant Medical Research},
author = { Ioannis Basdekis and Christos Kloukinas and Carlos Agostinho and Ioannis Vezakis and Andreia Pimenta and Luigi Gallo and Georgios Spanoudakis},
doi = {10.1109/DRCN57075.2023.10108370},
isbn = {978-1-66547-598-3},
year = {2023},
date = {2023-04-01},
urldate = {2023-04-01},
booktitle = {2023 19th International Conference on the Design of Reliable Communication Networks (DRCN)},
pages = {1--6},
publisher = {IEEE},
address = {Vilanova i la Geltru, Spain},
abstract = {Pseudonymisation is a data protection technique often used to protect the privacy of individuals when their personal data are being used for research purposes. Not only is it a key ingredient of the General Data Protection Regulation (GDPR) that requires organisations to ensure that the personal data they process is handled in a secure manner, but it is particularly important in assisting medical research given that often relies on sensitive personal data, since it reduces the risk that medical data could be misused or mishandled. For managing their medical data, it is important to ensure that such data are protected against unauthorised access, and can be reutilised in an anonymous fashion, while still authorised personnel is able to identify the study participant that some data belong to (e.g., for personalised interventions, technical alerts, technical support). In addition, the re-identification of a study participant is a pre-requisite for exercising their rights under the GDPR, since it assists organisations in meeting GDPR requirements (such as the right to access, rectify and portability of data). We argue that the application of pseudonymisation is particularly effective when considered during the early stages (Privacy by Design) of digital services implementation, as well as when defining the complementary to these organizational procedures. Aim of this paper is to present the way in which the pseudonymisation mechanism of the SMART BEAR H2020 project supports the triptych of research activities conducted within the context of an observational medical study, legal obligations arising from the regulatory framework for the protection of personal data, and reutilisation of data for research purposes. Evidence-based security and privacy assessments will be conducted on two different H2020 projects to evaluate such privacy practice.},
keywords = {GDPR, Healthcare, Security},
pubstate = {published},
tppubtype = {inproceedings}
}
Pseudonymisation is a data protection technique often used to protect the privacy of individuals when their personal data are being used for research purposes. Not only is it a key ingredient of the General Data Protection Regulation (GDPR) that requires organisations to ensure that the personal data they process is handled in a secure manner, but it is particularly important in assisting medical research given that often relies on sensitive personal data, since it reduces the risk that medical data could be misused or mishandled. For managing their medical data, it is important to ensure that such data are protected against unauthorised access, and can be reutilised in an anonymous fashion, while still authorised personnel is able to identify the study participant that some data belong to (e.g., for personalised interventions, technical alerts, technical support). In addition, the re-identification of a study participant is a pre-requisite for exercising their rights under the GDPR, since it assists organisations in meeting GDPR requirements (such as the right to access, rectify and portability of data). We argue that the application of pseudonymisation is particularly effective when considered during the early stages (Privacy by Design) of digital services implementation, as well as when defining the complementary to these organizational procedures. Aim of this paper is to present the way in which the pseudonymisation mechanism of the SMART BEAR H2020 project supports the triptych of research activities conducted within the context of an observational medical study, legal obligations arising from the regulatory framework for the protection of personal data, and reutilisation of data for research purposes. Evidence-based security and privacy assessments will be conducted on two different H2020 projects to evaluate such privacy practice.
Palombi, Tommaso; Galli, Federica; Giancamilli, Francesco; D’Amico, Monica; Alivernini, Fabio; Gallo, Luigi; Neroni, Pietro; Predazzi, Marco; Pietro, Giuseppe De; Lucidi, Fabio; Giordano, Antonio; Chirico, Andrea
The role of sense of presence in expressing cognitive abilities in a virtual reality task: an initial validation study Journal Article
In: Scientific Reports, vol. 13, no. 1, pp. 13396, 2023, ISSN: 2045-2322.
Abstract | Links | BibTeX | Tags: Healthcare, Mild Cognitive Impairment, Virtual Reality
@article{palombi2023role,
title = {The role of sense of presence in expressing cognitive abilities in a virtual reality task: an initial validation study},
author = { Tommaso Palombi and Federica Galli and Francesco Giancamilli and Monica D’Amico and Fabio Alivernini and Luigi Gallo and Pietro Neroni and Marco Predazzi and Giuseppe De Pietro and Fabio Lucidi and Antonio Giordano and Andrea Chirico},
url = {https://www.nature.com/articles/s41598-023-40510-0},
doi = {10.1038/s41598-023-40510-0},
issn = {2045-2322},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
journal = {Scientific Reports},
volume = {13},
number = {1},
pages = {13396},
publisher = {Nature Publishing Group UK London},
abstract = {There is a raised interest in literature to use Virtual Reality (VR) technology as an assessment tool for cognitive domains. One of the essential advantages of transforming tests in an immersive virtual environment is the possibility of automatically calculating the test's score, a time-consuming process under natural conditions. Although the characteristics of VR can deliver different degrees of immersion in a virtual environment, the sense of presence could jeopardize the evolution of these practices. The sense of presence results from a complex interaction between human, contextual factors, and the VR environment. The present study has two aims: firstly, it contributes to the validation of a virtual version of the naturalistic action test (i.e., virtual reality action test); second, it aims to evaluate the role of sense of presence as a critical booster of the expression of cognitive abilities during virtual reality tasks. The study relies on healthy adults tested in virtual and real conditions in a cross-over research design. The study's results support the validity of the virtual reality action test. Furthermore, two structural equation models are tested to comprehend the role of sense of presence as a moderator in the relationship between cognitive abilities and virtual task performance.},
keywords = {Healthcare, Mild Cognitive Impairment, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
There is a raised interest in literature to use Virtual Reality (VR) technology as an assessment tool for cognitive domains. One of the essential advantages of transforming tests in an immersive virtual environment is the possibility of automatically calculating the test's score, a time-consuming process under natural conditions. Although the characteristics of VR can deliver different degrees of immersion in a virtual environment, the sense of presence could jeopardize the evolution of these practices. The sense of presence results from a complex interaction between human, contextual factors, and the VR environment. The present study has two aims: firstly, it contributes to the validation of a virtual version of the naturalistic action test (i.e., virtual reality action test); second, it aims to evaluate the role of sense of presence as a critical booster of the expression of cognitive abilities during virtual reality tasks. The study relies on healthy adults tested in virtual and real conditions in a cross-over research design. The study's results support the validity of the virtual reality action test. Furthermore, two structural equation models are tested to comprehend the role of sense of presence as a moderator in the relationship between cognitive abilities and virtual task performance.
2022
Melillo, Antonio; Chirico, Andrea; Pietro, Giuseppe De; Gallo, Luigi; Caggianese, Giuseppe; Barone, Daniela; Laurentiis, Michelino De; Giordano, Antonio
Virtual Reality Rehabilitation Systems for Cancer Survivors: A Narrative Review of the Literature Journal Article
In: Cancers, vol. 14, no. 13, pp. 3163, 2022, ISSN: 2072-6694.
Abstract | Links | BibTeX | Tags: Healthcare, Virtual Reality
@article{melilloVirtualRealityRehabilitation2022a,
title = {Virtual Reality Rehabilitation Systems for Cancer Survivors: A Narrative Review of the Literature},
author = { Antonio Melillo and Andrea Chirico and Giuseppe De Pietro and Luigi Gallo and Giuseppe Caggianese and Daniela Barone and Michelino De Laurentiis and Antonio Giordano},
doi = {10.3390/cancers14133163},
issn = {2072-6694},
year = {2022},
date = {2022-06-01},
urldate = {2023-05-10},
journal = {Cancers},
volume = {14},
number = {13},
pages = {3163},
abstract = {Rehabilitation plays a crucial role in cancer care, as the functioning of cancer survivors is frequently compromised by impairments that can result from the disease itself but also from the long-term sequelae of the treatment. Nevertheless, the current literature shows that only a minority of patients receive physical and/or cognitive rehabilitation. This lack of rehabilitative care is a consequence of many factors, one of which includes the transportation issues linked to disability that limit the patient's access to rehabilitation facilities. The recent COVID-19 pandemic has further shown the benefits of improving telemedicine and home-based rehabilitative interventions to facilitate the delivery of rehabilitation programs when attendance at healthcare facilities is an obstacle. In recent years, researchers have been investigating the benefits of the application of virtual reality to rehabilitation. Virtual reality is shown to improve adherence and training intensity through gamification, allow the replication of real-life scenarios, and stimulate patients in a multimodal manner. In our present work, we offer an overview of the present literature on virtual reality-implemented cancer rehabilitation. The existence of wide margins for technological development allows us to expect further improvements, but more randomized controlled trials are needed to confirm the hypothesis that VRR may improve adherence rates and facilitate telerehabilitation.},
keywords = {Healthcare, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
Rehabilitation plays a crucial role in cancer care, as the functioning of cancer survivors is frequently compromised by impairments that can result from the disease itself but also from the long-term sequelae of the treatment. Nevertheless, the current literature shows that only a minority of patients receive physical and/or cognitive rehabilitation. This lack of rehabilitative care is a consequence of many factors, one of which includes the transportation issues linked to disability that limit the patient's access to rehabilitation facilities. The recent COVID-19 pandemic has further shown the benefits of improving telemedicine and home-based rehabilitative interventions to facilitate the delivery of rehabilitation programs when attendance at healthcare facilities is an obstacle. In recent years, researchers have been investigating the benefits of the application of virtual reality to rehabilitation. Virtual reality is shown to improve adherence and training intensity through gamification, allow the replication of real-life scenarios, and stimulate patients in a multimodal manner. In our present work, we offer an overview of the present literature on virtual reality-implemented cancer rehabilitation. The existence of wide margins for technological development allows us to expect further improvements, but more randomized controlled trials are needed to confirm the hypothesis that VRR may improve adherence rates and facilitate telerehabilitation.
Montalbano, Laura; Gallo, Luigi; Ferrante, Giuliana; Malizia, Velia; Cilluffo, Giovanna; Fasola, Salvatore; Alesi, Marianna; Grutta, Stefania La
Serious Games: A New Approach to Foster Information and Practices About Covid-19? Journal Article
In: Frontiers in Robotics and AI, vol. 9, pp. 830950, 2022, ISSN: 2296-9144.
Abstract | Links | BibTeX | Tags: Healthcare, Serious game
@article{montalbanoSeriousGamesNew2022,
title = {Serious Games: A New Approach to Foster Information and Practices About Covid-19?},
author = { Laura Montalbano and Luigi Gallo and Giuliana Ferrante and Velia Malizia and Giovanna Cilluffo and Salvatore Fasola and Marianna Alesi and Stefania La Grutta},
doi = {10.3389/frobt.2022.830950},
issn = {2296-9144},
year = {2022},
date = {2022-05-01},
urldate = {2023-05-10},
journal = {Frontiers in Robotics and AI},
volume = {9},
pages = {830950},
abstract = {The current Covid-19 pandemic poses an unprecedented global challenge in the field of education and training. As we have seen, the lack of proper information about the virus and its transmission has forced the general population and healthcare workers to rapidly acquire knowledge and learn new practices. Clearly, a well-informed population is more likely to adopt the correct precautionary measures, thus reducing the transmission of the infection; likewise, properly educated healthcare workers are better equipped to manage the emergency. However, the need to maintain physical distancing has made it impossible to provide in-presence information and training. In this regard, new technologies have proved to be an invaluable resource by facilitating distance learning. Indeed, e-learning offers significant advantages because it does not require the physical presence of learners and teachers. This innovative method applied to serious games has been considered potentially effective in enabling rapid and large-scale dissemination of information and learning through content interactivity. We will review studies that have observed the development and use of serious games to foster information and practices about Covid-19 aimed at promoting behavioral changes in the population and the healthcare personnel involved on the front line.},
keywords = {Healthcare, Serious game},
pubstate = {published},
tppubtype = {article}
}
The current Covid-19 pandemic poses an unprecedented global challenge in the field of education and training. As we have seen, the lack of proper information about the virus and its transmission has forced the general population and healthcare workers to rapidly acquire knowledge and learn new practices. Clearly, a well-informed population is more likely to adopt the correct precautionary measures, thus reducing the transmission of the infection; likewise, properly educated healthcare workers are better equipped to manage the emergency. However, the need to maintain physical distancing has made it impossible to provide in-presence information and training. In this regard, new technologies have proved to be an invaluable resource by facilitating distance learning. Indeed, e-learning offers significant advantages because it does not require the physical presence of learners and teachers. This innovative method applied to serious games has been considered potentially effective in enabling rapid and large-scale dissemination of information and learning through content interactivity. We will review studies that have observed the development and use of serious games to foster information and practices about Covid-19 aimed at promoting behavioral changes in the population and the healthcare personnel involved on the front line.
Esposito, Ciro; Autorino, Giuseppe; Iervolino, Anna; Vozzella, Emilia Anna; Cerulo, Mariapina; Esposito, Giovanni; Coppola, Vincenzo; Carulli, Roberto; Cortese, Giuseppe; Gallo, Luigi; Escolino, Maria
In: Journal of Laparoendoscopic & Advanced Surgical Techniques, vol. 32, no. 2, pp. 197–203, 2022, ISSN: 1092-6429, 1557-9034.
Abstract | Links | BibTeX | Tags: Healthcare, Pediatric Surgery, Randomized Clinical Trial, Virtual Reality
@article{espositoEfficacyVirtualReality2022,
title = {Efficacy of a Virtual Reality Program in Pediatric Surgery to Reduce Anxiety and Distress Symptoms in the Preoperative Phase: A Prospective Randomized Clinical Trial},
author = { Ciro Esposito and Giuseppe Autorino and Anna Iervolino and Emilia Anna Vozzella and Mariapina Cerulo and Giovanni Esposito and Vincenzo Coppola and Roberto Carulli and Giuseppe Cortese and Luigi Gallo and Maria Escolino},
doi = {10.1089/lap.2021.0566},
issn = {1092-6429, 1557-9034},
year = {2022},
date = {2022-02-01},
urldate = {2023-03-15},
journal = {Journal of Laparoendoscopic & Advanced Surgical Techniques},
volume = {32},
number = {2},
pages = {197--203},
abstract = {Background: Virtual reality (VR) experience is the most adopted form of video-gaming to reduce preoperative anxiety. This prospective randomized clinical trial aimed to examine the feasibility and efficacy of preoperative VR experience in children undergoing elective surgery. Materials and Methods: All patients older than 13 years and scheduled for elective surgery between March and June 2021 were enrolled. Preoperative VR experience consisted in watching a 5-minute video using a head-mounted display. Four parameters were evaluated and compared between the two groups: (1) patient heart rate (HR) before anesthesia; (2) patient evaluation of preoperative anxiety using facial affective scale (FAS); (3) anesthesiologist evaluation of preoperative anxiety using FAS; and (4) subjective stress scoring using a 5-item Likert-type scale. Results: A total of 40 patients (23 boys) with a median age of 14.5 years (range 12– 17) participated in the study. The patients were randomized in two groups, each of 20 patients, according to preoperative VR experience: VR group (G1) and control group (G2). No adverse events related to VR occurred. The patient median HR was significantly lower in G1 (72 bpm) than in G2 (101 bpm) (P = .001). The very relaxed/relaxed face selection rate using FAS was significantly higher in G1 than in G2, in both patient and anesthesiologist evaluations (P = .001). Finally, the subjective patient scoring of operating room experience was significantly greater in G1 [4.6 $pm$ 0.4] than in G2 [2.15 $pm$ 1.07] (P = .001). Conclusions: Our preliminary results showed that VR is safe and effective to relieve anxiety and improve relaxation in the preoperative period in pediatric patients undergoing elective surgery. The VR experience resulted in decreased overall anxiety and increased overall positive affect during the preoperative period in VR group compared with the control group. Further studies are needed to investigate this technology in the postoperative phase and on a larger patient cohort.},
keywords = {Healthcare, Pediatric Surgery, Randomized Clinical Trial, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
Background: Virtual reality (VR) experience is the most adopted form of video-gaming to reduce preoperative anxiety. This prospective randomized clinical trial aimed to examine the feasibility and efficacy of preoperative VR experience in children undergoing elective surgery. Materials and Methods: All patients older than 13 years and scheduled for elective surgery between March and June 2021 were enrolled. Preoperative VR experience consisted in watching a 5-minute video using a head-mounted display. Four parameters were evaluated and compared between the two groups: (1) patient heart rate (HR) before anesthesia; (2) patient evaluation of preoperative anxiety using facial affective scale (FAS); (3) anesthesiologist evaluation of preoperative anxiety using FAS; and (4) subjective stress scoring using a 5-item Likert-type scale. Results: A total of 40 patients (23 boys) with a median age of 14.5 years (range 12– 17) participated in the study. The patients were randomized in two groups, each of 20 patients, according to preoperative VR experience: VR group (G1) and control group (G2). No adverse events related to VR occurred. The patient median HR was significantly lower in G1 (72 bpm) than in G2 (101 bpm) (P = .001). The very relaxed/relaxed face selection rate using FAS was significantly higher in G1 than in G2, in both patient and anesthesiologist evaluations (P = .001). Finally, the subjective patient scoring of operating room experience was significantly greater in G1 [4.6 $pm$ 0.4] than in G2 [2.15 $pm$ 1.07] (P = .001). Conclusions: Our preliminary results showed that VR is safe and effective to relieve anxiety and improve relaxation in the preoperative period in pediatric patients undergoing elective surgery. The VR experience resulted in decreased overall anxiety and increased overall positive affect during the preoperative period in VR group compared with the control group. Further studies are needed to investigate this technology in the postoperative phase and on a larger patient cohort.
Agostinho, Carlos; Pimenta, Andreia; Marques, Maria; Tsiouris, Kostas M.; Kalatzis, Fanis; Nikitas, Christos; Iliadou, Eleftheria; Occhipinti, Mattia; Kouris, Ioannis; Koutsouris, Dimitrios; Basdekis, Ioannis; Koloutsu, Konstantina; Gallo, Luigi; Pietro, Giuseppe De; Jardim-Goncalves, Ricardo
Healthier and Independent Living of the Elderly: Interoperability in a Cross-Project Pilot Proceedings Article
In: 2022 Interoperability for Enterprise Systems and Applications Workshops, CEUR Workshop Proceedings, Valencia, Spain, 2022.
Abstract | Links | BibTeX | Tags: Healthcare, Interoperability
@inproceedings{agostinhoHealthierIndependentLiving2022,
title = {Healthier and Independent Living of the Elderly: Interoperability in a Cross-Project Pilot},
author = { Carlos Agostinho and Andreia Pimenta and Maria Marques and Kostas M. Tsiouris and Fanis Kalatzis and Christos Nikitas and Eleftheria Iliadou and Mattia Occhipinti and Ioannis Kouris and Dimitrios Koutsouris and Ioannis Basdekis and Konstantina Koloutsu and Luigi Gallo and Giuseppe De Pietro and Ricardo {Jardim-Goncalves}},
url = {https://ceur-ws.org/Vol-3214/WS7Paper2.pdf},
year = {2022},
date = {2022-01-01},
urldate = {2022-01-01},
booktitle = {2022 Interoperability for Enterprise Systems and Applications Workshops},
volume = {3214},
publisher = {CEUR Workshop Proceedings},
address = {Valencia, Spain},
abstract = {The ageing of the population creates new heterogeneous challenges for age-friendly living. The progressive decline in physical and cognitive skills tends to prevent elderly people from performing basic instrumental activities of daily living and there is a growing interest in technology for aging support. Digital health today can be exercised by anyone owning a smartphone and parameters such as heart rate, step counts, calorie intake, sleep quality, can be collected and used not only to monitor and improve the individual's health condition but also to prevent illnesses. However, for the benefits of e-health to take place, digital health data, either Electronic Health Records (EHR) or sensor data from the IoMT, must be shared, maintaining privacy and security requirements but unlocking the potential for research an innovation throughout EU. This paper demonstrates the added value of such interoperability requirements, and a form of accomplishing them through a cross-project pilot.},
keywords = {Healthcare, Interoperability},
pubstate = {published},
tppubtype = {inproceedings}
}
The ageing of the population creates new heterogeneous challenges for age-friendly living. The progressive decline in physical and cognitive skills tends to prevent elderly people from performing basic instrumental activities of daily living and there is a growing interest in technology for aging support. Digital health today can be exercised by anyone owning a smartphone and parameters such as heart rate, step counts, calorie intake, sleep quality, can be collected and used not only to monitor and improve the individual's health condition but also to prevent illnesses. However, for the benefits of e-health to take place, digital health data, either Electronic Health Records (EHR) or sensor data from the IoMT, must be shared, maintaining privacy and security requirements but unlocking the potential for research an innovation throughout EU. This paper demonstrates the added value of such interoperability requirements, and a form of accomplishing them through a cross-project pilot.
Gaglio, Giuseppe Fulvio; Augello, Agnese; Caggianese, Giuseppe; Gallo, Luigi
Modellazione 3D di avatar per il Serious Game SMILER Technical Report
no. RT-ICAR-NA-2022-01, 2022.
Abstract | Links | BibTeX | Tags: Healthcare, Human computer interaction, Touchless interaction, Virtual Reality
@techreport{gaglioModellazione3DDi2022,
title = {Modellazione 3D di avatar per il Serious Game SMILER},
author = { Giuseppe Fulvio Gaglio and Agnese Augello and Giuseppe Caggianese and Luigi Gallo},
url = {https://intranet.icar.cnr.it/wp-content/uploads/2022/07/RT-ICAR-NA-2022-01.pdf},
year = {2022},
date = {2022-01-01},
urldate = {2022-01-01},
number = {RT-ICAR-NA-2022-01},
abstract = {Il presente documento illustra la progettazione e la realizzazione di un avatar per il serious game previsto nell'ambito del progetto guillemotleft SMILER guillemotright - Serious gaMes as emerging e-health Interventions for young people with neurologicaL or rEspiratory disoRders. Dopo una breve introduzione del progetto, verranno descritte le tecniche e gli strumenti utilizzati per la modellazione 3D dell'avatar.},
keywords = {Healthcare, Human computer interaction, Touchless interaction, Virtual Reality},
pubstate = {published},
tppubtype = {techreport}
}
Il presente documento illustra la progettazione e la realizzazione di un avatar per il serious game previsto nell'ambito del progetto guillemotleft SMILER guillemotright - Serious gaMes as emerging e-health Interventions for young people with neurologicaL or rEspiratory disoRders. Dopo una breve introduzione del progetto, verranno descritte le tecniche e gli strumenti utilizzati per la modellazione 3D dell'avatar.
Melillo, Antonio; Maiorano, Patrizia; Rachedi, Sarah; Caggianese, Giuseppe; Gragnano, Elisabetta; Gallo, Luigi; Pietro, Giuseppe De; Guida, Maurizio; Giordano, Antonio; Chirico, Andrea
In: Critical Reviews in Eukaryotic Gene Expression, vol. 32, no. 2, pp. 61–89, 2022, ISSN: 1045-4403.
Abstract | Links | BibTeX | Tags: Healthcare, Virtual Reality
@article{melilloLaborAnalgesiaSystematic2022a,
title = {Labor Analgesia: A Systematic Review and Meta-Analysis of Non-Pharmacological Complementary and Alternative Approaches to Pain during First Stage of Labor},
author = { Antonio Melillo and Patrizia Maiorano and Sarah Rachedi and Giuseppe Caggianese and Elisabetta Gragnano and Luigi Gallo and Giuseppe De Pietro and Maurizio Guida and Antonio Giordano and Andrea Chirico},
doi = {10.1615/CritRevEukaryotGeneExpr.2021039986},
issn = {1045-4403},
year = {2022},
date = {2022-01-01},
urldate = {2023-05-10},
journal = {Critical Reviews in Eukaryotic Gene Expression},
volume = {32},
number = {2},
pages = {61--89},
abstract = {The aim of the study was to conduct a meta-analysis to evaluate the efficacy of non-invasive and non-pharmacological techniques on labor first-stage pain intensity. Literature databases were searched from inception to May 2021, and research was expanded through the screening of previous systematic reviews. Inclusion criteria were: (1) population: women in first stage of labor; (2) intervention: non-pharmacological, non-invasive, or minimally invasive intrapartum analgesic techniques alternative and/or complementary to pharmacological analgesia; (3) comparison: routine intrapartum care or placebos; (4) outcomes: subjective pain intensity; and (5) study design: randomized controlled trial. Risk of bias of included studies was investigated, data analysis was performed using R version 3.5.1. Effect size was calculated as difference between the control and experimental groups at posttreatment in terms of mean pain score. A total of 63 studies were included, for a total of 6146 patients (3468 in the experimental groups and 2678 in the control groups). Techniques included were massage (n = 11), birth balls (n = 5) mind-body interventions (n = 8), heat application (n = 12), music therapy (n = 9), dance therapy (n = 2), acupressure (n = 16), and transcutaneous electrical nerve stimulation (TENS) (n = 8). The present review found significant evidence in support of the use of complementary and alternative medicine for labor analgesia, and different methods showed different impact. However, more high-quality trials are needed.},
keywords = {Healthcare, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
The aim of the study was to conduct a meta-analysis to evaluate the efficacy of non-invasive and non-pharmacological techniques on labor first-stage pain intensity. Literature databases were searched from inception to May 2021, and research was expanded through the screening of previous systematic reviews. Inclusion criteria were: (1) population: women in first stage of labor; (2) intervention: non-pharmacological, non-invasive, or minimally invasive intrapartum analgesic techniques alternative and/or complementary to pharmacological analgesia; (3) comparison: routine intrapartum care or placebos; (4) outcomes: subjective pain intensity; and (5) study design: randomized controlled trial. Risk of bias of included studies was investigated, data analysis was performed using R version 3.5.1. Effect size was calculated as difference between the control and experimental groups at posttreatment in terms of mean pain score. A total of 63 studies were included, for a total of 6146 patients (3468 in the experimental groups and 2678 in the control groups). Techniques included were massage (n = 11), birth balls (n = 5) mind-body interventions (n = 8), heat application (n = 12), music therapy (n = 9), dance therapy (n = 2), acupressure (n = 16), and transcutaneous electrical nerve stimulation (TENS) (n = 8). The present review found significant evidence in support of the use of complementary and alternative medicine for labor analgesia, and different methods showed different impact. However, more high-quality trials are needed.
Peretokin, Vadim; Basdekis, Ioannis; Kouris, Ioannis; Maggesi, Jonatan; Sicuranza, Mario; Su, Qiqi; Acebes, Alberto; Bucur, Anca; Mukkala, Vinod; Pozdniakov, Konstantin; Kloukinas, Christos; Koutsouris, Dimitrios; Iliadou, Elefteria; Leontsinis, Ioannis; Gallo, Luigi; Pietro, Giuseppe De; Spanoudakis, George
Overview of the SMART-BEAR Technical Infrastructure Best Paper Proceedings Article
In: Proceedings of the 8th International Conference on Information and Communication Technologies for Ageing Well and E-Health, pp. 117–125, SCITEPRESS - Science and Technology Publications, Online, 2022, ISBN: 978-989-758-566-1.
Abstract | Links | BibTeX | Tags: Artificial intelligence, Balance Disorder, Cardiovascular Disease, Cloud computing, Evidence-based, GDPR, Healthcare, Hearing Loss, HL7 FHIR, Interoperability, Semantics
@inproceedings{peretokinOverviewSMARTBEARTechnical2022,
title = {Overview of the SMART-BEAR Technical Infrastructure},
author = { Vadim Peretokin and Ioannis Basdekis and Ioannis Kouris and Jonatan Maggesi and Mario Sicuranza and Qiqi Su and Alberto Acebes and Anca Bucur and Vinod Mukkala and Konstantin Pozdniakov and Christos Kloukinas and Dimitrios Koutsouris and Elefteria Iliadou and Ioannis Leontsinis and Luigi Gallo and Giuseppe De Pietro and George Spanoudakis},
doi = {10.5220/0011082700003188},
isbn = {978-989-758-566-1},
year = {2022},
date = {2022-01-01},
urldate = {2022-01-01},
booktitle = {Proceedings of the 8th International Conference on Information and Communication Technologies for Ageing Well and E-Health},
pages = {117--125},
publisher = {SCITEPRESS - Science and Technology Publications},
address = {Online},
abstract = {This paper describes a cloud-based platform that offers evidence-based, personalised interventions powered by Artificial Intelligence to help support efficient remote monitoring and clinician-driven guidance to people over 65 who suffer or are at risk of hearing loss, cardiovascular diseases, cognitive impairments, balance disorders, and mental health issues. This platform has been developed within the SMART-BEAR integrated project to power its large-scale clinical pilots and comprises a standards-based data harmonisation and management layer, a security component, a Big Data Analytics system, a Clinical Decision Support tool, and a dashboard component for efficient data collection across the pilot sites.},
keywords = {Artificial intelligence, Balance Disorder, Cardiovascular Disease, Cloud computing, Evidence-based, GDPR, Healthcare, Hearing Loss, HL7 FHIR, Interoperability, Semantics},
pubstate = {published},
tppubtype = {inproceedings}
}
This paper describes a cloud-based platform that offers evidence-based, personalised interventions powered by Artificial Intelligence to help support efficient remote monitoring and clinician-driven guidance to people over 65 who suffer or are at risk of hearing loss, cardiovascular diseases, cognitive impairments, balance disorders, and mental health issues. This platform has been developed within the SMART-BEAR integrated project to power its large-scale clinical pilots and comprises a standards-based data harmonisation and management layer, a security component, a Big Data Analytics system, a Clinical Decision Support tool, and a dashboard component for efficient data collection across the pilot sites.
2021
Ferrante, Giuliana; Vitale, Gianpaolo; Licari, Amelia; Montalbano, Laura; Pilato, Giovanni; Infantino, Ignazio; Augello, Agnese; Grutta, Stefania La
Social Robots and Therapeutic Adherence: A New Challenge in Pediatric Asthma? Journal Article
In: Paediatric Respiratory Reviews, vol. 40, pp. 46–51, 2021, ISSN: 15260542.
Abstract | Links | BibTeX | Tags: Asthma, Healthcare, Robotics, Social Agents, Social Robots
@article{ferranteSocialRobotsTherapeutic2021,
title = {Social Robots and Therapeutic Adherence: A New Challenge in Pediatric Asthma?},
author = { Giuliana Ferrante and Gianpaolo Vitale and Amelia Licari and Laura Montalbano and Giovanni Pilato and Ignazio Infantino and Agnese Augello and Stefania La Grutta},
doi = {10.1016/j.prrv.2020.11.001},
issn = {15260542},
year = {2021},
date = {2021-01-01},
journal = {Paediatric Respiratory Reviews},
volume = {40},
pages = {46--51},
abstract = {Social Robots are used in different contexts and, in healthcare, they are better known as Socially Assistive Robots. In the context of asthma, the use of Socially Assistive Robots has the potential to increase motivation and engagement to treatment. Other positive roles proposed for Socially Assistive Robots are to provide education, training regarding treatments, and feedback to patients. This review evaluates emerging interventions for improving treatment adherence in pediatric asthma, focusing on the possible future role of social robots in the clinical practice. textcopyright 2020 Elsevier Ltd},
keywords = {Asthma, Healthcare, Robotics, Social Agents, Social Robots},
pubstate = {published},
tppubtype = {article}
}
Social Robots are used in different contexts and, in healthcare, they are better known as Socially Assistive Robots. In the context of asthma, the use of Socially Assistive Robots has the potential to increase motivation and engagement to treatment. Other positive roles proposed for Socially Assistive Robots are to provide education, training regarding treatments, and feedback to patients. This review evaluates emerging interventions for improving treatment adherence in pediatric asthma, focusing on the possible future role of social robots in the clinical practice. textcopyright 2020 Elsevier Ltd
2020
Chirico, Andrea; Giovannetti, Tania; Neroni, Pietro; Simone, Stephanie; Gallo, Luigi; Galli, Federica; Giancamilli, Francesco; Predazzi, Marco; Lucidi, Fabio; Pietro, Giuseppe De; Giordano, Antonio
In: Frontiers in Psychology, vol. 11, pp. 123, 2020, ISSN: 1664-1078.
Abstract | Links | BibTeX | Tags: Elderly, Healthcare, Monitoring, Virtual Reality
@article{chiricoVirtualRealityAssessment2020,
title = {Virtual Reality for the Assessment of Everyday Cognitive Functions in Older Adults: An Evaluation of the Virtual Reality Action Test and Two Interaction Devices in a 91-Year-Old Woman},
author = { Andrea Chirico and Tania Giovannetti and Pietro Neroni and Stephanie Simone and Luigi Gallo and Federica Galli and Francesco Giancamilli and Marco Predazzi and Fabio Lucidi and Giuseppe De Pietro and Antonio Giordano},
doi = {10.3389/fpsyg.2020.00123},
issn = {1664-1078},
year = {2020},
date = {2020-01-01},
journal = {Frontiers in Psychology},
volume = {11},
pages = {123},
abstract = {Performance-based functional tests for the evaluation of daily living activities demonstrate strong psychometric properties and solve many of the limitations associated with self- and informant-report questionnaires. Virtual reality (VR) technology, which has gained interest as an effective medium for administering interventions in the context of healthcare, has the potential to minimize the time-demands associated with the administration and scoring of performance-based assessments. To date, efforts to develop VR systems for assessment of everyday function in older adults generally have relied on non-immersive systems. The aim of the present study was to evaluate the feasibility of an immersive VR environment for the assessment of everyday function in older adults. We present a detailed case report of an elderly woman who performed an everyday activity in an immersive VR context (Virtual Reality Action Test) with two different types of interaction devices (controller vs. sensor). VR performance was compared to performance of the same task with real objects outside of the VR system (Real Action Test). Comparisons were made on several dimensions, including (1) quality of task performance (e.g., order of task steps, errors, use and speed of hand movements); (2) subjective impression (e.g., attitudes), and (3) physiological markers of stress. Subjective impressions of performance with the different controllers also were compared for presence, cybersickness, and usability. Results showed that the participant was capable of using controllers and sensors to manipulate objects in a purposeful and goal-directed manner in the immersive VR paradigm. She performed the everyday task similarly across all conditions. She reported no cybersickness and even indicated that interactions in the VR environment were pleasant and relaxing. Thus, immersive VR is a feasible approach for function assessment even with older adults who might have very limited computer experience, no prior VR exposure, average educational experiences, and mild cognitive difficulties. Because of inherent limitations of single case reports (e.g., unknown generalizability, potential practice effects, etc.), group studies are needed to establish the full psychometric properties of the Virtual Reality Action Test.},
keywords = {Elderly, Healthcare, Monitoring, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
Performance-based functional tests for the evaluation of daily living activities demonstrate strong psychometric properties and solve many of the limitations associated with self- and informant-report questionnaires. Virtual reality (VR) technology, which has gained interest as an effective medium for administering interventions in the context of healthcare, has the potential to minimize the time-demands associated with the administration and scoring of performance-based assessments. To date, efforts to develop VR systems for assessment of everyday function in older adults generally have relied on non-immersive systems. The aim of the present study was to evaluate the feasibility of an immersive VR environment for the assessment of everyday function in older adults. We present a detailed case report of an elderly woman who performed an everyday activity in an immersive VR context (Virtual Reality Action Test) with two different types of interaction devices (controller vs. sensor). VR performance was compared to performance of the same task with real objects outside of the VR system (Real Action Test). Comparisons were made on several dimensions, including (1) quality of task performance (e.g., order of task steps, errors, use and speed of hand movements); (2) subjective impression (e.g., attitudes), and (3) physiological markers of stress. Subjective impressions of performance with the different controllers also were compared for presence, cybersickness, and usability. Results showed that the participant was capable of using controllers and sensors to manipulate objects in a purposeful and goal-directed manner in the immersive VR paradigm. She performed the everyday task similarly across all conditions. She reported no cybersickness and even indicated that interactions in the VR environment were pleasant and relaxing. Thus, immersive VR is a feasible approach for function assessment even with older adults who might have very limited computer experience, no prior VR exposure, average educational experiences, and mild cognitive difficulties. Because of inherent limitations of single case reports (e.g., unknown generalizability, potential practice effects, etc.), group studies are needed to establish the full psychometric properties of the Virtual Reality Action Test.
Chirico, Andrea; Maiorano, Patrizia; Indovina, Paola; Milanese, Carla; Giordano, Giovan Giacomo; Alivernini, Fabio; Iodice, Giovanni; Gallo, Luigi; Pietro, Giuseppe De; Lucidi, Fabio; Botti, Gerardo; Laurentiis, Michelino De; Giordano, Antonio
In: Journal of cellular physiology, vol. 235, no. 6, pp. 5353–5362, 2020, ISSN: 1097-4652.
Abstract | Links | BibTeX | Tags: Cancer, Chemotherapy, Healthcare, Virtual Reality
@article{chiricoVirtualRealityMusic2020,
title = {Virtual Reality and Music Therapy as Distraction Interventions to Alleviate Anxiety and Improve Mood States in Breast Cancer Patients during Chemotherapy},
author = { Andrea Chirico and Patrizia Maiorano and Paola Indovina and Carla Milanese and Giovan Giacomo Giordano and Fabio Alivernini and Giovanni Iodice and Luigi Gallo and Giuseppe De Pietro and Fabio Lucidi and Gerardo} {Botti and Michelino De Laurentiis and Antonio Giordano},
doi = {10.1002/jcp.29422},
issn = {1097-4652},
year = {2020},
date = {2020-01-01},
journal = {Journal of cellular physiology},
volume = {235},
number = {6},
pages = {5353--5362},
abstract = {Psychological distress is a common consequence of breast cancer diagnosis and treatment and could further exacerbate therapy side effects. Interventions increasing treatment tolerance are crucial to improve both patients' quality of life and adherence to therapies. Virtual reality (VR) has emerged as an effective distraction tool for different medical procedures. Here, we assessed the efficacy of immersive and interactive VR in alleviating chemotherapy-related psychological distress in a cohort of Italian breast cancer patients, also comparing its effects with those of music therapy (MT). Thirty patients were included in the VR group, 30 in the MT group, and 34 in the control group, consisting of patients receiving standard care during chemotherapy. Our data suggest that both VR and MT are useful interventions for alleviating anxiety and for improving mood states in breast cancer patients during chemotherapy. Moreover, VR seems more effective than MT in relieving anxiety, depression, and fatigue.},
keywords = {Cancer, Chemotherapy, Healthcare, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
Psychological distress is a common consequence of breast cancer diagnosis and treatment and could further exacerbate therapy side effects. Interventions increasing treatment tolerance are crucial to improve both patients' quality of life and adherence to therapies. Virtual reality (VR) has emerged as an effective distraction tool for different medical procedures. Here, we assessed the efficacy of immersive and interactive VR in alleviating chemotherapy-related psychological distress in a cohort of Italian breast cancer patients, also comparing its effects with those of music therapy (MT). Thirty patients were included in the VR group, 30 in the MT group, and 34 in the control group, consisting of patients receiving standard care during chemotherapy. Our data suggest that both VR and MT are useful interventions for alleviating anxiety and for improving mood states in breast cancer patients during chemotherapy. Moreover, VR seems more effective than MT in relieving anxiety, depression, and fatigue.
2019
Caggianese, Giuseppe; Cuomo, Salvatore; Esposito, Massimo; Franceschini, Marco; Gallo, Luigi; Infarinato, Francesco; Minutolo, Aniello; Piccialli, Francesco; Romano, Paola
Serious Games and In-Cloud Data Analytics for the Virtualization and Personalization of Rehabilitation Treatments Journal Article
In: IEEE Transactions on Industrial Informatics, vol. 15, no. 1, pp. 517–526, 2019, ISSN: 1941-0050.
Abstract | Links | BibTeX | Tags: Artificial intelligence, Healthcare, Natural User Interfaces, Rehabilitation, Serious game, Stroke
@article{caggianeseSeriousGamesInCloud2019,
title = {Serious Games and In-Cloud Data Analytics for the Virtualization and Personalization of Rehabilitation Treatments},
author = { Giuseppe Caggianese and Salvatore Cuomo and Massimo Esposito and Marco Franceschini and Luigi Gallo and Francesco Infarinato and Aniello Minutolo and Francesco Piccialli and Paola Romano},
doi = {10.1109/TII.2018.2856097},
issn = {1941-0050},
year = {2019},
date = {2019-01-01},
journal = {IEEE Transactions on Industrial Informatics},
volume = {15},
number = {1},
pages = {517--526},
abstract = {During the last years, the significant increase in the number of patients in need of rehabilitation has generated an unsustainable economic impact on healthcare systems, implying a reduction in therapeutic supervision and support for each patient. To address this problem, this paper proposes a telerehabilitation system based on serious games and in-cloud data analytics services, in accordance with Industry 4.0 design principles regarding modularity, service orientation, decentralization, virtualization, and real-time capability. The system, specialized for poststroke patients, comprises components for real-time acquisition of patient's motor data and a decision support service for their analysis. Raw data, reports, and recommendations are made available on the cloud to clinical operators to remotely assess rehabilitation outcomes and dynamically improve therapies. Furthermore, the results of a pilot study on the clinical impact deriving from the adoption of the proposed solution, and of a qualitative analysis about its acceptance, are presented and discussed.},
keywords = {Artificial intelligence, Healthcare, Natural User Interfaces, Rehabilitation, Serious game, Stroke},
pubstate = {published},
tppubtype = {article}
}
During the last years, the significant increase in the number of patients in need of rehabilitation has generated an unsustainable economic impact on healthcare systems, implying a reduction in therapeutic supervision and support for each patient. To address this problem, this paper proposes a telerehabilitation system based on serious games and in-cloud data analytics services, in accordance with Industry 4.0 design principles regarding modularity, service orientation, decentralization, virtualization, and real-time capability. The system, specialized for poststroke patients, comprises components for real-time acquisition of patient's motor data and a decision support service for their analysis. Raw data, reports, and recommendations are made available on the cloud to clinical operators to remotely assess rehabilitation outcomes and dynamically improve therapies. Furthermore, the results of a pilot study on the clinical impact deriving from the adoption of the proposed solution, and of a qualitative analysis about its acceptance, are presented and discussed.
2018
Caggianese, Giuseppe; Chirico, Andrea; Pietro, Giuseppe De; Gallo, Luigi; Giordano, Antonio; Predazzi, Marco; Neroni, Pietro
Towards a Virtual Reality Cognitive Training System for Mild Cognitive Impairment and Alzheimer's Disease Patients Proceedings Article
In: 2018 32nd International Conference on Advanced Information Networking and Applications Workshops (WAINA), pp. 663–667, 2018.
Abstract | Links | BibTeX | Tags: Alzheimer's disease, Cognitive training, Dementia, Healthcare, Mild Cognitive Impairment, Monitoring, Training, Virtual Reality
@inproceedings{caggianeseVirtualRealityCognitive2018,
title = {Towards a Virtual Reality Cognitive Training System for Mild Cognitive Impairment and Alzheimer's Disease Patients},
author = { Giuseppe Caggianese and Andrea Chirico and Giuseppe De Pietro and Luigi Gallo and Antonio Giordano and Marco Predazzi and Pietro Neroni},
doi = {10.1109/WAINA.2018.00164},
year = {2018},
date = {2018-05-01},
booktitle = {2018 32nd International Conference on Advanced Information Networking and Applications Workshops (WAINA)},
pages = {663--667},
abstract = {The rapid growth of the aged population has stimulated research directed at designing interventions to support the associated social, economic and health challenges in an elderly population. Environmental interventions, like cognitive rehabilitation, stimulation and training can significantly improve cognitive functioning, so mitigating the cognitive decline. In this area, the adoption of state-of-the-art virtual reality technologies can provide a cost-effective, flexible and comprehensive solution for realizing complex cognitive training environments. With the aim of preserving mnestic and logical-praxic functions of patients with MCI or Alzheimer's disease at the early stages, in this paper we describe our ongoing work in designing a novel, fullyequipped virtual reality cognitive training system. The system is characterized by a high degree of realism and interactivity, to provide the patient with an adequate sense of presence within the virtual environment. Moreover, it is able to monitor the patient's biomedical signals and collect quantitative data on the training sessions, so allowing the therapist to analyze and tailor the training strategies to the patient.},
keywords = {Alzheimer's disease, Cognitive training, Dementia, Healthcare, Mild Cognitive Impairment, Monitoring, Training, Virtual Reality},
pubstate = {published},
tppubtype = {inproceedings}
}
The rapid growth of the aged population has stimulated research directed at designing interventions to support the associated social, economic and health challenges in an elderly population. Environmental interventions, like cognitive rehabilitation, stimulation and training can significantly improve cognitive functioning, so mitigating the cognitive decline. In this area, the adoption of state-of-the-art virtual reality technologies can provide a cost-effective, flexible and comprehensive solution for realizing complex cognitive training environments. With the aim of preserving mnestic and logical-praxic functions of patients with MCI or Alzheimer's disease at the early stages, in this paper we describe our ongoing work in designing a novel, fullyequipped virtual reality cognitive training system. The system is characterized by a high degree of realism and interactivity, to provide the patient with an adequate sense of presence within the virtual environment. Moreover, it is able to monitor the patient's biomedical signals and collect quantitative data on the training sessions, so allowing the therapist to analyze and tailor the training strategies to the patient.
Ciampi, Mario; Gallo, Luigi; Pietro, Giuseppe De
MITO: An Advanced Toolkit for Medical Imaging Processing and Visualization Technical Report
no. RT-ICAR-NA-2018-02, 2018.
Abstract | BibTeX | Tags: Healthcare, Human computer interaction, Touchless interaction, Virtual Reality
@techreport{ciampiMITOAdvancedToolkit2018,
title = {MITO: An Advanced Toolkit for Medical Imaging Processing and Visualization},
author = { Mario Ciampi and Luigi Gallo and Giuseppe De Pietro},
year = {2018},
date = {2018-01-01},
number = {RT-ICAR-NA-2018-02},
abstract = {This technical report presents MITO, an open software environment for medical image acquisition, processing, visualization, and navigation. The system is able to interact with PACS servers conforming to the DICOM 3.0 standard in order to retrieve and send radiological image data. Acquired 2D images can be manipulated with MITO for basic operations and advanced processing, like image segmentation, region extraction, image fusion, 3D reconstructions. Advanced 2D and 3D user interfaces allow users to interact with medical images and volumes through various input devices or in a completely touchless way. The high number of downloads of the software system, along with its widespread use in numerous experimental scenarios, show the high extensiveness and performance of the features developed.},
keywords = {Healthcare, Human computer interaction, Touchless interaction, Virtual Reality},
pubstate = {published},
tppubtype = {techreport}
}
This technical report presents MITO, an open software environment for medical image acquisition, processing, visualization, and navigation. The system is able to interact with PACS servers conforming to the DICOM 3.0 standard in order to retrieve and send radiological image data. Acquired 2D images can be manipulated with MITO for basic operations and advanced processing, like image segmentation, region extraction, image fusion, 3D reconstructions. Advanced 2D and 3D user interfaces allow users to interact with medical images and volumes through various input devices or in a completely touchless way. The high number of downloads of the software system, along with its widespread use in numerous experimental scenarios, show the high extensiveness and performance of the features developed.
Indovina, Paola; Barone, Daniela; Gallo, Luigi; Chirico, Andrea; Pietro, Giuseppe De; Giordano, Antonio
Virtual Reality as a Distraction Intervention to Relieve Pain and Distress During Medical Procedures: A Comprehensive Literature Review Journal Article
In: The Clinical Journal of Pain, vol. 34, no. 9, 2018, ISSN: 0749-8047.
Abstract | BibTeX | Tags: Chemotherapy, Healthcare, Pain, Virtual Reality
@article{indovinaVirtualRealityDistraction2018,
title = {Virtual Reality as a Distraction Intervention to Relieve Pain and Distress During Medical Procedures: A Comprehensive Literature Review},
author = { Paola Indovina and Daniela Barone and Luigi Gallo and Andrea Chirico and Giuseppe De Pietro and Antonio Giordano},
issn = {0749-8047},
year = {2018},
date = {2018-01-01},
journal = {The Clinical Journal of Pain},
volume = {34},
number = {9},
abstract = {Objectives: This review aims to provide a framework for evaluating the utility of virtual reality (VR) as a distraction intervention to alleviate pain and distress during medical procedures. We first describe the theoretical bases underlying the VR analgesic and anxiolytic effects and define the main factors contributing to its efficacy, which largely emerged from studies on healthy volunteers. Then, we provide a comprehensive overview of the clinical trials using VR distraction during different medical procedures, such as burn injury treatments, chemotherapy, surgery, dental treatment, and other diagnostic and therapeutic procedures. Methods: A broad literature search was performed using as main terms ``virtual reality,'' ``distraction,'' and ``pain.'' No date limit was applied and all the retrieved studies on immersive VR distraction during medical procedures were selected. Results: VR has proven to be effective in reducing procedural pain, as almost invariably observed even in patients subjected to extremely painful procedures, such as patients with burn injuries undergoing wound care, and physical therapy. Moreover, VR seemed to decrease cancer-related symptoms in different settings, including during chemotherapy. Only mild and infrequent side effects were observed. Discussion: Despite these promising results, future long-term randomized controlled trials with larger sample sizes and evaluating not only self-report measures but also physiological variables are needed. Further studies are also required both to establish predictive factors to select patients who can benefit from VR distraction and to design hardware/software systems tailored to the specific needs of different patients and able to provide the greatest distraction at the lowest cost.},
keywords = {Chemotherapy, Healthcare, Pain, Virtual Reality},
pubstate = {published},
tppubtype = {article}
}
Objectives: This review aims to provide a framework for evaluating the utility of virtual reality (VR) as a distraction intervention to alleviate pain and distress during medical procedures. We first describe the theoretical bases underlying the VR analgesic and anxiolytic effects and define the main factors contributing to its efficacy, which largely emerged from studies on healthy volunteers. Then, we provide a comprehensive overview of the clinical trials using VR distraction during different medical procedures, such as burn injury treatments, chemotherapy, surgery, dental treatment, and other diagnostic and therapeutic procedures. Methods: A broad literature search was performed using as main terms ``virtual reality,'' ``distraction,'' and ``pain.'' No date limit was applied and all the retrieved studies on immersive VR distraction during medical procedures were selected. Results: VR has proven to be effective in reducing procedural pain, as almost invariably observed even in patients subjected to extremely painful procedures, such as patients with burn injuries undergoing wound care, and physical therapy. Moreover, VR seemed to decrease cancer-related symptoms in different settings, including during chemotherapy. Only mild and infrequent side effects were observed. Discussion: Despite these promising results, future long-term randomized controlled trials with larger sample sizes and evaluating not only self-report measures but also physiological variables are needed. Further studies are also required both to establish predictive factors to select patients who can benefit from VR distraction and to design hardware/software systems tailored to the specific needs of different patients and able to provide the greatest distraction at the lowest cost.
2017
Caggianese, Giuseppe; Calabrese, Mariaconsiglia; Gallo, Luigi; Sannino, Giovanna; Vecchione, Carmine
Cardiac Surgery Rehabilitation System (CSRS) for a Personalized Support to Patients Proceedings Article
In: 2017 13th International Conference on Signal-Image Technology Internet-Based Systems (SITIS), pp. 83–90, 2017.
Abstract | Links | BibTeX | Tags: Biomedical monitoring, Cognitive and physical monitoring, Games, Healthcare, Monitoring, Patient-centered environment, Rehabilitation, Sensor systems, Surgery, Tracking
@inproceedings{caggianeseCardiacSurgeryRehabilitation2017,
title = {Cardiac Surgery Rehabilitation System (CSRS) for a Personalized Support to Patients},
author = { Giuseppe Caggianese and Mariaconsiglia Calabrese and Luigi Gallo and Giovanna Sannino and Carmine Vecchione},
doi = {10.1109/SITIS.2017.24},
year = {2017},
date = {2017-12-01},
booktitle = {2017 13th International Conference on Signal-Image Technology Internet-Based Systems (SITIS)},
pages = {83--90},
abstract = {For a successful rehabilitation after cardiac surgery, it is crucial to have a carefully personalized, structured, and supervised physiotherapy program. Due to erroneous or unsupervised physiotherapy, nearly 50% of surgeries fail. Researchers have tried to leverage advances in wearable sensors and motion tracking to build affordable, automated, and customizable rehabilitation systems that help both therapists and patients during physiotherapy sessions. In this paper, we present a patient-centered cardiac surgery rehabilitation system (CSRS) for the personalization of the patient's physiotherapy for the early post-operative period. The system has been designed to interconnect different acquisition sensors and to be distributed on different stations in order to be able to continuously monitor the patient's vital signs and evaluate her/his cognitive and motor abilities in real time.},
keywords = {Biomedical monitoring, Cognitive and physical monitoring, Games, Healthcare, Monitoring, Patient-centered environment, Rehabilitation, Sensor systems, Surgery, Tracking},
pubstate = {published},
tppubtype = {inproceedings}
}
For a successful rehabilitation after cardiac surgery, it is crucial to have a carefully personalized, structured, and supervised physiotherapy program. Due to erroneous or unsupervised physiotherapy, nearly 50% of surgeries fail. Researchers have tried to leverage advances in wearable sensors and motion tracking to build affordable, automated, and customizable rehabilitation systems that help both therapists and patients during physiotherapy sessions. In this paper, we present a patient-centered cardiac surgery rehabilitation system (CSRS) for the personalization of the patient's physiotherapy for the early post-operative period. The system has been designed to interconnect different acquisition sensors and to be distributed on different stations in order to be able to continuously monitor the patient's vital signs and evaluate her/his cognitive and motor abilities in real time.
Caggianese, Giuseppe; Calabrese, Mariaconsiglia; Maio, Vincenzo De; Pietro, Giuseppe De; Faggiano, Armando; Gallo, Luigi; Sannino, Giovanna; Vecchione, Carmine
A Rehabilitation System for Post-operative Heart Surgery Proceedings Article
In: Pietro, Giuseppe De; Gallo, Luigi; Howlett, Robert J.; Jain, Lakhmi C. (Ed.): Intelligent Interactive Multimedia Systems and Services 2017, pp. 554–564, Springer International Publishing, 2017, ISBN: 978-3-319-59480-4.
Abstract | Links | BibTeX | Tags: Healthcare, Microsoft kinect, Rehabilitation, Serious game, Telemonitoring, Unity 3D
@inproceedings{caggianeseRehabilitationSystemPostoperative2017,
title = {A Rehabilitation System for Post-operative Heart Surgery},
author = { Giuseppe Caggianese and Mariaconsiglia Calabrese and Vincenzo De Maio and Giuseppe De Pietro and Armando Faggiano and Luigi Gallo and Giovanna Sannino and Carmine Vecchione},
editor = { Giuseppe De Pietro and Luigi Gallo and Robert J. Howlett and Lakhmi C. Jain},
doi = {10.1007/978-3-319-59480-4_55},
isbn = {978-3-319-59480-4},
year = {2017},
date = {2017-01-01},
booktitle = {Intelligent Interactive Multimedia Systems and Services 2017},
pages = {554--564},
publisher = {Springer International Publishing},
series = {Smart Innovation, Systems and Technologies},
abstract = {Supervised exercise programs are an important aspect of the rehabilitation process of patients after heart surgery. A large number of factors must be taken into account before implementing a rehabilitation program. These mainly consist in the patient's cognitive and physical capabilities after the operation and the expectations of recovery. A rehabilitation program should also be designed in relation to the stage of the healing process, with the therapist selecting the best sequence of exercises while taking into account the most appropriate effort level for the patient. This paper describes a customizable rehabilitation system for the early post-operative period, useful for the performance of an assessment of the patients, through an evaluation of their cognitive and motor abilities, and for a dynamic personalization of the therapy sessions focused on patient needs.},
keywords = {Healthcare, Microsoft kinect, Rehabilitation, Serious game, Telemonitoring, Unity 3D},
pubstate = {published},
tppubtype = {inproceedings}
}
Supervised exercise programs are an important aspect of the rehabilitation process of patients after heart surgery. A large number of factors must be taken into account before implementing a rehabilitation program. These mainly consist in the patient's cognitive and physical capabilities after the operation and the expectations of recovery. A rehabilitation program should also be designed in relation to the stage of the healing process, with the therapist selecting the best sequence of exercises while taking into account the most appropriate effort level for the patient. This paper describes a customizable rehabilitation system for the early post-operative period, useful for the performance of an assessment of the patients, through an evaluation of their cognitive and motor abilities, and for a dynamic personalization of the therapy sessions focused on patient needs.
Gallo, Luigi; Marra, Ivana
Rapporto tecnico contabile (01/06/2015– 30/11/2016) Progetto SmartCARE Technical Report
no. RT-ICAR-NA-2017-03, 2017.
Abstract | BibTeX | Tags: Healthcare, Human computer interaction, Touchless interaction
@techreport{galloRapportoTecnicoContabile2017,
title = {Rapporto tecnico contabile (01/06/2015– 30/11/2016) Progetto SmartCARE},
author = { Luigi Gallo and Ivana Marra},
year = {2017},
date = {2017-01-01},
number = {RT-ICAR-NA-2017-03},
abstract = {Scopo di questo lavoro `e quello di presentare un report sulle attivit`a svolte dal soggetto beneficiario Istituto di Calcolo e Reti ad Alte Prestazioni (ICAR) del Consiglio Nazionale delle Ricerche (CNR) per la rendicontazione tecnico-amministrativa, con breve descrizione delle attivit`a di ricerca svolte e dettaglio dei costi sostenuti nel periodo 01/06/2015- 30/11/2016, nell'ambito del progetto SmartCARE ``Satellite enhanced Multi-channel ehealth Assistance for Remote Tele-rehabilitation and CAREgiving''- Proposal no. ITSLAB/ESA/ARTES/2014-1 - RFQ/ITT no. AO/1-5891/08/NL/US.},
keywords = {Healthcare, Human computer interaction, Touchless interaction},
pubstate = {published},
tppubtype = {techreport}
}
Scopo di questo lavoro `e quello di presentare un report sulle attivit`a svolte dal soggetto beneficiario Istituto di Calcolo e Reti ad Alte Prestazioni (ICAR) del Consiglio Nazionale delle Ricerche (CNR) per la rendicontazione tecnico-amministrativa, con breve descrizione delle attivit`a di ricerca svolte e dettaglio dei costi sostenuti nel periodo 01/06/2015- 30/11/2016, nell'ambito del progetto SmartCARE ``Satellite enhanced Multi-channel ehealth Assistance for Remote Tele-rehabilitation and CAREgiving''- Proposal no. ITSLAB/ESA/ARTES/2014-1 - RFQ/ITT no. AO/1-5891/08/NL/US.
2016
Adinolfi, Francesco; Caggianese, Giuseppe; Gallo, Luigi; Grosso, Juan; Infarinato, Francesco; Marchese, Nazzareno; Sale, Patrizio; Spaltro, Emiliano
SmartCARE - An ICT Platform in the Domain of Stroke Pathology to Manage Rehabilitation Treatment and Telemonitoring at Home Proceedings Article
In: Pietro, Giuseppe De; Gallo, Luigi; Howlett, Robert J.; Jain, Lakhmi C. (Ed.): Intelligent Interactive Multimedia Systems and Services 2016, pp. 39–49, Springer International Publishing Switzerland, 2016, ISBN: 978-3-319-39344-5 978-3-319-39345-2.
Abstract | Links | BibTeX | Tags: Healthcare, Microsoft band, Microsoft kinect, Rehabilitation, Serious game, Stroke, Telemonitoring, Unity 3D, Wearable devices
@inproceedings{adinolfiSmartCAREICTPlatform2016,
title = {SmartCARE - An ICT Platform in the Domain of Stroke Pathology to Manage Rehabilitation Treatment and Telemonitoring at Home},
author = { Francesco Adinolfi and Giuseppe Caggianese and Luigi Gallo and Juan Grosso and Francesco Infarinato and Nazzareno Marchese and Patrizio Sale and Emiliano Spaltro},
editor = { Giuseppe De Pietro and Luigi Gallo and Robert J. Howlett and Lakhmi C. Jain},
doi = {10.1007/978-3-319-39345-2_4},
isbn = {978-3-319-39344-5 978-3-319-39345-2},
year = {2016},
date = {2016-06-01},
urldate = {2016-12-06},
booktitle = {Intelligent Interactive Multimedia Systems and Services 2016},
volume = {55},
pages = {39--49},
publisher = {Springer International Publishing Switzerland},
series = {Smart Innovation, Systems and Technologies},
abstract = {This paper describes the SmartCARE ICT eco-system, which goal is to deliver advanced health collaboration services in the rehabilitation domain. The system provides a set of tools that enable the continuity of care at home to patients affected by stroke diseases. Moreover, by taking advantage of motion sensing-based serious games and virtual companions, the system can stimulate the patient at being more reactive both at neuro-motorial and neuro-cognitive levels.},
keywords = {Healthcare, Microsoft band, Microsoft kinect, Rehabilitation, Serious game, Stroke, Telemonitoring, Unity 3D, Wearable devices},
pubstate = {published},
tppubtype = {inproceedings}
}
This paper describes the SmartCARE ICT eco-system, which goal is to deliver advanced health collaboration services in the rehabilitation domain. The system provides a set of tools that enable the continuity of care at home to patients affected by stroke diseases. Moreover, by taking advantage of motion sensing-based serious games and virtual companions, the system can stimulate the patient at being more reactive both at neuro-motorial and neuro-cognitive levels.
Aprovitola, Andrea; Gallo, Luigi
Knee Bone Segmentation from MRI: A Classification and Literature Review Journal Article
In: Biocybernetics and Biomedical Engineering, vol. 36, no. 2, pp. 437–449, 2016, ISSN: 02085216.
Abstract | Links | BibTeX | Tags: Healthcare, Knee bone, MRI, Segmentation
@article{aprovitolaKneeBoneSegmentation2016,
title = {Knee Bone Segmentation from MRI: A Classification and Literature Review},
author = { Andrea Aprovitola and Luigi Gallo},
doi = {10.1016/j.bbe.2015.12.007},
issn = {02085216},
year = {2016},
date = {2016-01-01},
urldate = {2016-12-06},
journal = {Biocybernetics and Biomedical Engineering},
volume = {36},
number = {2},
pages = {437--449},
abstract = {Segmentation of cartilage from Magnetic Resonance (MR) images has evolved as a tool for the diagnosis of knee joint pathologies. However, accuracy and reproducibility of automated methods of cartilage segmentation may require the prior extraction of bone surfaces from MR imaging sequences specifically designed to evidence the cartilage and not the bone. Thus a priori knowledge of knee joint structures and fully automated segmentation methods are adopted to provide reliable detection of bone surfaces. In this paper, we review knee bone segmentation methods from MR images. We classified the methods proposed in literature according to the level of a priori knowledge, the level of automation and the level of manual user interaction. Furthermore we discuss the segmentation results in literature in relation to the MR sequences used to image the bone.},
keywords = {Healthcare, Knee bone, MRI, Segmentation},
pubstate = {published},
tppubtype = {article}
}
Segmentation of cartilage from Magnetic Resonance (MR) images has evolved as a tool for the diagnosis of knee joint pathologies. However, accuracy and reproducibility of automated methods of cartilage segmentation may require the prior extraction of bone surfaces from MR imaging sequences specifically designed to evidence the cartilage and not the bone. Thus a priori knowledge of knee joint structures and fully automated segmentation methods are adopted to provide reliable detection of bone surfaces. In this paper, we review knee bone segmentation methods from MR images. We classified the methods proposed in literature according to the level of a priori knowledge, the level of automation and the level of manual user interaction. Furthermore we discuss the segmentation results in literature in relation to the MR sequences used to image the bone.
2013
Gallo, Luigi; Placitelli, Alessio Pierluigi
High-Fidelity Visualization of Large Medical Datasets on Commodity Hardware Journal Article
In: ISRN Biomedical Engineering, vol. 2013, no. 892967, pp. 9, 2013, ISSN: 2314-6346.
Abstract | Links | BibTeX | Tags: GPU, Healthcare, Visualization
@article{galloHighfidelityVisualizationLarge2013,
title = {High-Fidelity Visualization of Large Medical Datasets on Commodity Hardware},
author = { Luigi Gallo and Alessio Pierluigi Placitelli},
doi = {10.1155/2013/892967},
issn = {2314-6346},
year = {2013},
date = {2013-01-01},
journal = {ISRN Biomedical Engineering},
volume = {2013},
number = {892967},
pages = {9},
abstract = {Recent advances in CT and MRI static and dynamic scanning techniques have led to great improvements in the resolution and size of volumetric medical datasets, and this trend is still ongoing.However, the explosion of dataset size prevents clinicians fromtaking advantage of an interactive, high-resolution exploration of volumetric medical data on commodity hardware, due to the memory constraints of modern graphics cards.This paper presents a hybrid CPU-GPU volume ray-casting method and some hybrid-based inspection tools aimed at providing interactive, medical-quality visualization using an ordinary desktop PC. Experimental results show that the hybrid method provides a near-interactive high-fidelity visualization of large medical datasets even if only limited hardware resources are available.},
keywords = {GPU, Healthcare, Visualization},
pubstate = {published},
tppubtype = {article}
}
Recent advances in CT and MRI static and dynamic scanning techniques have led to great improvements in the resolution and size of volumetric medical datasets, and this trend is still ongoing.However, the explosion of dataset size prevents clinicians fromtaking advantage of an interactive, high-resolution exploration of volumetric medical data on commodity hardware, due to the memory constraints of modern graphics cards.This paper presents a hybrid CPU-GPU volume ray-casting method and some hybrid-based inspection tools aimed at providing interactive, medical-quality visualization using an ordinary desktop PC. Experimental results show that the hybrid method provides a near-interactive high-fidelity visualization of large medical datasets even if only limited hardware resources are available.
2012
Gallo, Luigi; Placitelli, Alessio Pierluigi
Studio tecnologico per il porting di MITO (Medical Imaging TOolkit) su dispositivi mobili Technical Report
no. RT-ICAR-NA-2012-8, 2012.
Abstract | BibTeX | Tags: Healthcare, Human computer interaction
@techreport{galloStudioTecnologicoPorting2012,
title = {Studio tecnologico per il porting di MITO (Medical Imaging TOolkit) su dispositivi mobili},
author = { Luigi Gallo and Alessio Pierluigi Placitelli},
year = {2012},
date = {2012-09-01},
number = {RT-ICAR-NA-2012-8},
abstract = {Sono presentate tre strategie per il porting del software MITO su piattaforme mobile. La prima strategia, raccomandata, prevede l'uso della libreria VES (Kitware) per eseguire i render sul dispositivo, fornendo una comoda base di sviluppo limitandosi alle piattaforme supportate. La seconda strategia prevede l'uso delle tecnologie HTML5 e WebGL, eseguendo i render sul dispositivo, permettendo l'esecuzione del software su tutte le architetture che supportano tali standard. La terza ed ultima strategia, prevede lo sviluppo di un thin client per ciascuna piattaforma supportata che si appoggi ad una render farm remota per l'esecuzione dei calcoli grafici.},
keywords = {Healthcare, Human computer interaction},
pubstate = {published},
tppubtype = {techreport}
}
Sono presentate tre strategie per il porting del software MITO su piattaforme mobile. La prima strategia, raccomandata, prevede l'uso della libreria VES (Kitware) per eseguire i render sul dispositivo, fornendo una comoda base di sviluppo limitandosi alle piattaforme supportate. La seconda strategia prevede l'uso delle tecnologie HTML5 e WebGL, eseguendo i render sul dispositivo, permettendo l'esecuzione del software su tutte le architetture che supportano tali standard. La terza ed ultima strategia, prevede lo sviluppo di un thin client per ciascuna piattaforma supportata che si appoggi ad una render farm remota per l'esecuzione dei calcoli grafici.
Coronato, Antonio; Gallo, Luigi
Towards Abnormal Behavior Detection of Cognitive Impaired People Proceedings Article
In: 2012 IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOM Workshops), pp. 865–870, IEEE, Lugano, Switzerland, 2012, ISBN: 978-1-4673-0906-6.
Abstract | Links | BibTeX | Tags: Healthcare, Mild Cognitive Impairment
@inproceedings{coronatoAbnormalBehaviorDetection2012,
title = {Towards Abnormal Behavior Detection of Cognitive Impaired People},
author = { Antonio Coronato and Luigi Gallo},
doi = {10.1109/PerComW.2012.6197632},
isbn = {978-1-4673-0906-6},
year = {2012},
date = {2012-03-01},
booktitle = {2012 IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOM Workshops)},
pages = {865--870},
publisher = {IEEE},
address = {Lugano, Switzerland},
abstract = {The assessment of the general health status of people with cognitive impairment, and so the quality of drug therapy, requires reliable information about their daily lifestyle. Especially in the case of Alzheimer's Disease (AD) patients, the patients themselves or their primary caregivers may not be reliable in providing such information. This raises the demand for a new generation of intelligent, situation-aware environments able to collect, process and store information about patients' daily activities. In this paper, a new approach for the detection of abnormal behavior in AD patients is presented. Instead of relying on the identification of deviations from normal behaviors, the approach is based on the specification and runtime verification of the correctness properties of objects, which are visually recognized by means of non-intrusive RGB-D cameras. The Bigraphical reactive system is the formal method adopted to model the correctness properties; whereas, the runtime verification is performed by a specifically designed software component.},
keywords = {Healthcare, Mild Cognitive Impairment},
pubstate = {published},
tppubtype = {inproceedings}
}
The assessment of the general health status of people with cognitive impairment, and so the quality of drug therapy, requires reliable information about their daily lifestyle. Especially in the case of Alzheimer's Disease (AD) patients, the patients themselves or their primary caregivers may not be reliable in providing such information. This raises the demand for a new generation of intelligent, situation-aware environments able to collect, process and store information about patients' daily activities. In this paper, a new approach for the detection of abnormal behavior in AD patients is presented. Instead of relying on the identification of deviations from normal behaviors, the approach is based on the specification and runtime verification of the correctness properties of objects, which are visually recognized by means of non-intrusive RGB-D cameras. The Bigraphical reactive system is the formal method adopted to model the correctness properties; whereas, the runtime verification is performed by a specifically designed software component.